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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publikation
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019
Citraconic acid and derivatives thereof for use as a medicament
Publikation
Frank Pessler,
Fangfang Chen,
Moritz Winterhoff,
Konrad Büssow,
Wulf Blankenfeldt,
Anna Hirsch,
Walid A. M. Elgaher
(2024)
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold
Publikation
Khalifa H,
ElHady A,
Liu T,
Elgaher W,
Filhol-Cochet O,
Cochet C,
Abadi A,
Hamed M,
Abdel-Halim M,
Engel M
(2025)
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publikation
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publikation
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publikation
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publikation
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced mutasynthesis studies on the natural α-pyrone antibiotic myxopyronin from Myxococcus fulvus
Publikation
Sahner J,
Sucipto H,
Wenzel S,
Groh M,
Hartmann R,
Müller R
(2015)
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Publikation
Frank N,
Széles M,
Akone S,
Rasheed S,
Hüttel S,
Frewert S,
Hamed M,
Herrmann J,
Schuler S,
Hirsch A,
Müller R
(2021)
Molecules, 26, 16, 10.3390/molecules26164929
Molecules, 26, 16, 10.3390/molecules26164929
Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction
Publikation
Mancini F,
Unver M,
Elgaher W,
Jumde V,
Alhayek A,
Lukat P,
Herrmann J,
Witte M,
Köck M,
Blankenfeldt W,
Müller R,
Hirsch A
(2020)
Chem. Eur. J., 10.1002/chem.202002250
Chem. Eur. J., 10.1002/chem.202002250