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Researcher in Laboratory © HIPS

Jun Prof Dr Alexey Gurevich

About

Alexey Gurevich studied software engineering at St. Petersburg State Polytechnic University (BSc 2010, summa cum laude) and St. Petersburg Academic University of the Russian Academy of Sciences (MSc 2012, summa cum laude). In 2011, in the Prof. Pavel Pevzner group at the Academic University, he started focussing on algorithmic bioinformatics. The group later relocated to St. Petersburg State University where Alexey obtained a Ph.D. in bioinformatics in 2018. He worked at St. Petersburg University until 2022 with short research visits to the Pevzner lab at the University of California San Diego (2015 and 2016) and to the Kohlbacher lab at the University of Tübingen (2019, DAAD Fellowship). In July 2022, Alexey joined HIPS as a Junior Professor leading the Human-Microbe Systems Bioinformatics group.

Alexey's research focuses on creating efficient algorithms and software for handling noisy omics data. He contributed to the state-of-the-art SPAdes and QUAST genome assembly and analysis software and multiple computational methods for natural product discovery. These works are widely used and cited by the research community as exemplified by the inclusion of Alexey Gurevich in the Web of Science list of Highly Cited Researchers 2023.


2024

Decoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics

Schmartz G, Rehner J, Gund M, Keller V, Molano L, Rupf S, Hannig M, Berger T, Flockerzi E, Seitz B, …, Bals R, Keller A (2024)

Nat Commun 15 (1)DOI: 10.1038/s41467-024-52598-7

2023

ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome

Hirsch P, Tagirdzhanov A, Kushnareva A, Olkhovskii I, Graf S, Schmartz G, Hegemann J, Bozhüyük K, Rolf M, Keller A, Gurevich A (2023)

BookDOI: 10.1101/2023.09.18.558305

HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search

Lee Y, Guler M, Chigumba D, Wang S, Mittal N, Miller C, Krummenacher B, Liu H, Cao L, Kannan A, …, Kersten R, Mohimani H (2023)

Nat Commun 14 (1)DOI: 10.1038/s41467-023-39905-4

ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome

Hirsch P, Tagirdzhanov A, Kushnareva A, Olkhovskii I, Graf S, Schmartz G, Hegemann J, Bozhüyük K, Müller R, Keller A, Gurevich A (2023)

Nucleic Acids ResDOI: 10.1093/nar/gkad1086

WebQUAST: online evaluation of genome assemblies

Mikheenko A, Saveliev V, Hirsch P, Gurevich A (2023)

Nucleic Acids Res 51 (W1): 601-DOI: 10.1093/nar/gkad406

2022

NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

Leão T, Wang M, Da Silva R, Gurevich A, Bauermeister A, Gomes P, Brejnrod A, Glukhov E, Aron A, Louwen J, …, Bandeira N, Dorrestein P (2022)

PNAS nexus 1 (5)DOI: 10.1093/pnasnexus/pgac257

NPvis: An Interactive Visualizer of Peptidic Natural Product-MS/MS Matches

Kunyavskaya O, Mikheenko A, Gurevich A (2022)

Metabolites 12 (8)DOI: 10.3390/metabo12080706